Molecular Test Listing

Molecular Requisition

THROMBOSIS RISK PANEL:

Venous thromboembolism is a worldwide health problem resulting in significant illness and death. Both genetic as well as environmental (e.g. smoking and oral contraceptives) factors contribute to the incidence of the disease. Defects in natural clotting components such as Factor V, Prothrombin, MTHFR, & HPA1 represent the best known risk factors for clotting risk and venous thromboembolism. 

In order to expedite diagnosis, reduce the total cost of testing, and improve the ease of ordering, these tests have been combined into a single panel. For details of each condition, please refer to the individual tests.

 

REASONS FOR REFERRAL:
  • To determine the potential cause of unexplained thrombosis in children or adults.
  • Patients undergoing surgery especially the potentially high-risk class of women taking estrogen supplements.
  • Evaluation of individuals before initiation of oral contraceptives.

TESTING METHODOLOGY:

  • PCR amplification of the region including the mutation, followed by mutation specific restriction enzyme digestion.

SPECIMEN REQUIREMENTS:
  • Blood EDTA (purple top) tubes:  

            Newborn: minimum 1-2 mL          

            Child/Adult: prefer 2 tubes of 3-5 mL

  • Prenatal testing: Please contact the laboratory for instructions.

  • A Molecular Genetics Laboratory Test Requisition must accompany the specimen. Contact the Molecular Laboratory at 918-502-1721 to obtain further information.

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    TURNAROUND TIME:     8 working days

    CPT CODES: